Welcome to Biophotonics and Nano Enigneering Laboratory at Seoul National University. BINEL is established in August 2006 to deliver various technological innovations through multidiciplinary research in photononics and bio/micro/nanotechnology. With firm base on photonics and micro/nanofabrication, our research interest spans in a wide range of topics such as nanobiotechnology, BioMems, micro total analysis systems and microfluidics.

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Introduction to BiNEL  /   Introduction to BiNEL Research

We are recruiting undergraduate students who are interested in structural color display using Biomemtic and self-assembly.

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Contact Information:

Address: 301-1117, Seoul National University, Shillim-dong, Kwanak-gu, Seoul 151-744, South Korea

Tel: +82-2-880-1737 Fax: +82-2-885-4459

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Cover page on Nature Materials 2010. 8 [read] 

News&Views in Nature Materials 2010. 8 [read]


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Encoded particles have a demonstrated value for multiplexed high-throughput bioassays such as drug discovery and clinical diagnostics. In diverse samples, the ability to use a large number of distinct identification codes on assay particles is important to increase throughput. Proper handling schemes are also needed to readout these codes on free-floating probe microparticles. Here we create vivid, free-floating structural colour particles with multi-axis rotational control using a colour-tunable magnetic material and a new printing method. Our colour-barcoded magnetic microparticles offer a coding capacity easily into the billions with distinct magnetic handling capabilities including active positioning for code readouts and active stirring for improved reaction kinetics in microscale environments5. A DNA hybridization assay is done using the colour-barcoded magnetic microparticles to demonstrate multiplexing capabilities.

Structural Color Printing on Nature Photonics 2009. 9 [read]


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Many creatures in nature, such as butterflies and peacocks, display unique brilliant colours, known as ‘structural colours’, which result from the interaction of light with periodic nanostructures on their surfaces. Mimicking such nanostructures found in nature, however, requires state-of-the-art nanofabrication techniques that are slow, expensive and not scalable. In this article, we demonstrate high-resolution patterning of multiple structural colours within seconds, based on successive tuning and fixing of colour using a single material along with a maskless lithography system. We have invented a material called ‘M-Ink’, the colour of which is tunable by magnetically changing the periodicity of the nanostructure and fixable by photochemically immobilizing those structures in a polymer network. We also demonstrate a flexible photonic crystal for the realization of structural colour printing. The simple, controllable and scalable structural colour printing scheme presented may have a significant impact on colour production for general consumer goods. 


Inside Cover and Hot articles on Lab on a Chip 2009. 7 [read]


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We demonstrate the microfluidic sorting of directionally oriented (anisotropic) microstructures by their orientational state in solution using the concept of railed microfluidics. After being injected into a microfluidic channel, the microstructures rotate and flip in various directions. In order to sort microstructures in an organized way, we designed the microstructures and the microchannel to allow for orientation-based control of microstructure movement. In order to sort microstructures based on their rotation, we used a wedge shaped fin on the microstructures and a Y-shaped railed microfluidic channel. For sorting flipped particles, we use a double-railed microfluidic channel that has grooves on both its top and bottom surfaces. By integrating the two sorting methods we demonstrated high throughput, autonomous sorting into four different orientational states: unrotated–unflipped, rotated–unflipped, unrotated–flipped, and rotated–flipped. Here we not only demonstrate orientational assembly of directionally dependent microstructures, but also present design considerations for future work


Front Cover and Hot articles on Lab on a Chip 2009. 6 [read]


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3D fabrication of hybrid microstructures is demonstrated using optofluidic maskless lithography and a membrane-controlled height-tunable microfluidic channel. The method allows for high-throughput synthesis of hybrid 3D microstructures and in situ biomaterial patterning.


Cover page on Nature Materials 2008. 7 [read]

Research Highlights in Nature 2008. 6. 26 [read]


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 Nature Materials, July 2008     Assembly using railed microfluidics

A technique for the self-assembly of polymeric microstructures, which works by using a guiding 'rail' mechanism, is reported online this week in Nature Materials. The method could be used for manufacturing two-dimensional patterns of living cells for tissue engineering and manipulating silicon devices for microchip packaging.
On the micrometre scale, conventional assembly techniques such as robotics are often not applicable, and can result in errors in the final product. Sunghoon Kwon and colleagues devised a way to guide the assembly of microstructures within microfluidic channels, and make complex structures composed of more than 50 individual ones. All the microstructures used at the start of the process are incorporated in the product and different shapes can also be guided to specific locations, allowing the construction of two-dimensional representations of, for example, the Eiffel Tower, a Greek temple and a computer keyboard.
The method works by introducing a groove or 'rail' into the top surface of the channels and a complementary shape in the polymeric microstructure. In contrast to other fluidic assembly routes, the structures are guided along the rail rather than moving in the exact direction of fluid flow in the channel.

fluidic self-assembly

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droplet rotation2

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droplet rotation

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